If you’ve just received the P-Shot—or you’re considering it—you might be wondering what happens after treatment. Will you feel different? When do results kick in? Is it truly life-changing, or just hype? The good news is that many men report not only improved sexual function but also increased energy, self-confidence, and a new sense of control over their wellness.

At Genesis Lifestyle Medicine, we’ve guided countless patients through the P-Shot experience—from first consultation to long-term success. In this article, we walk you through what to expect both immediately after treatment and in the months that follow so you can better understand how this innovative therapy could improve your life.

Immediately after the P-Shot…

Right after receiving the P-Shot, you can expect a few noticeable effects—both physical and mental. The procedure is quick and relatively painless, and many men walk out feeling hopeful and energized. Here’s what typically follows in the hours and days after treatment.

Mild swelling or sensitivity

Because the P-Shot involves injecting platelet-rich plasma (PRP) into targeted areas, a mild degree of swelling, tingling, or sensitivity is normal. This is a sign that your body has entered the regenerative phase, delivering growth factors and stem cell activation to the tissue. Most of this resolves within 24 to 48 hours.

A renewed sense of confidence

It may sound surprising, but many men report a psychological lift right after the procedure. Knowing that you've taken a proactive step toward better performance, improved intimacy, and overall well-being can have an immediate effect on self-esteem and emotional health, even before the full physical results appear.

A slight increase in firmness

Some patients experience a mild improvement in firmness or size within the first few days. While this is not the final result, it's often a motivating sign that the body is already responding to the PRP’s regenerative potential. However, you must be consistent with your treatment and attend all follow-up sessions to optimize the results.

Starting your post-treatment care routine

Your Genesis Lifestyle Medicine provider will likely recommend using a penile pump in the days following the P-Shot. This helps evenly distribute the PRP throughout the tissue, encourages healthy blood flow, and supports tissue expansion. You may also be advised to avoid vigorous physical or sexual activity for 24-48 hours.

Long-term effects of P-Shot…

The most exciting changes tend to unfold gradually in the weeks and months after the injection. The P-Shot is curated not just to provide a short-term boost, but to enhance long-term function and satisfaction through your body’s natural repair mechanisms.

Stronger, longer-lasting erections

As the PRP stimulates blood vessel growth and nerve regeneration, many patients notice a dramatic improvement in erectile strength, stamina, and control. This effect usually becomes noticeable after three to four weeks and can continue to improve over time. For some, the results peak around 8-12 weeks post-treatment.

Improved sensitivity and pleasure

The P-Shot’s regenerative properties often lead to enhanced sensation and more pleasurable intimacy. By rejuvenating nerve endings and encouraging new tissue growth, the treatment can restore sensitivity that may have diminished due to age or other factors.

Increased penile size (in some cases)

While not the primary goal of the P-Shot, some men do report a modest increase in length or girth due to improved circulation and cellular growth. This is typically a secondary effect and may vary from person to person, but when it occurs, it’s seen as a welcome bonus.

Better urinary function

Men with mild urinary incontinence or weak flow due to aging prostate issues may also notice improved urinary control following P-Shot treatment. Enhanced tissue strength and increased blood flow in the area may support better urinary health and bladder control.

Enhanced overall wellness and energy

As sexual confidence improves, it often has a ripple effect on other parts of life. Many men report feeling more energetic, motivated, and positive overall. This renewed vitality can boost performance not just in the bedroom but also in your career, workouts, and relationships.

Ongoing improvements with follow-up care

For maximum results, your Genesis Lifestyle Medicine provider may recommend a combination approach, such as pairing the P-Shot with GAINSWave therapy, hormone optimization, or lifestyle modifications. These integrated treatments can accelerate tissue healing, support hormonal balance, and extend the benefits of your P-Shot for years to come.

Rediscover what it means to feel like yourself again

The journey after the P-Shot is a gradual, regenerative process that can redefine your energy, self-esteem, and sexual wellness. From the immediate post-treatment sensations to the lasting changes in function, sensation, and confidence, the results speak for themselves. You’re not just recovering performance—you’re reclaiming a vital part of your life.

At Genesis Lifestyle Medicine, we’re here to guide you through every step of the process. If you’re ready to experience life after the P-Shot—energized, confident, and renewed—schedule your consultation today. A new, revitalized you is closer than you think.